Sanna, S; Li, BS; Mulas, A; Sidore, C; Kang, HM; Jackson, AU; Piras, MG; Usala, G; Maninchedda, G; Sassu, A; Serra, F; Palmas, MA; Wood, WH; Njølstad, Inger; Laakso, M; Hveem, Kristian; Tuomilehto, J; Lakka, TA; Rauramaa, R; Boehnke, M; Cucca, F; Uda, M; Schlessinger, D; Nagaraja, R; Abecasis, GR (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Complex trait genome-wide association studies (GWAS) provide an efficient strategy for evaluating large numbers of common variants in large numbers of individuals and for identifying trait-associated variants. Nevertheless, GWAS often leave much of the trait heritability unexplained. We hypothesized that some of this unexplained heritability might be due to common and rare variants that reside in ...